Assessment of adherence level of patients on anticoagulant therapy in a tertiary healthcare facility in Uyo, Nigeria

Authors

  • Ekwere T. A. Department of Haematology, University of Uyo/University of Uyo Teaching Hospital, Akwa Ibom State, Nigeria
  • Ekanem A. M.
  • Benson S. M.

Keywords:

Adherence, Anticoagulant, Venous thromboembolism

Abstract

Background: Anticoagulants are highly effective in preventing venous thromboembolism and remains the main stay of treatment. However, strict adherence to medication is essential for maximizing treatment.
Objectives: the objectives of this study, were to determine the adherence rate and factors that may influence adherence to anticoagulant therapy among patients on anticoagulant at a tertiary healthcare facility in Uyo, Nigeria.
Methodology: This was a cross-sectional study. Fifty-nine consented adult patients on anticoagulant therapy were recruited consecutively into the study. A structured self-administered questionnaire was used to obtain information on respondents sociodemographic characteristics, indications for anticoagulation and types of anticoagulant used. An 8-item Morisky Medication Adherence Scale (MMAS-8) was used to assess patient’s adherence to anticoagulation therapy.
Results: The mean age of respondents was 55.4±13.5 years. Thirty-three (55.9%) were males while 26 (44.1%) were females. The most common indication for anticoagulant use was for treatment of deep vein thrombosis (78%). The direct oral anticoagulant (DOAC) was the most frequently used anticoagulant (76.3%), and majority (44.1%) had treatment for 3 months. Overall, 49.1% of the respondents had unacceptably low level of adherence while 10% had high level adherence to anticoagulant use. The female gender and the duration of anticoagulant were significantly associated with the level of adherence.
Conclusion: Adherence to anticoagulant use among respondents in this study was suboptimal. The female gender and the duration of anticoagulant were significantly associated with the level of adherence.

Additional Files

Published

01-01-2021

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