Subarachnoid lavage following inadvertent intrathecal injection of tranexamic acid

Salahu D; Abdullahi MM; Abdullahi H; Adeleke N; Adesope S; Aliyu LD; Hassan MM; Alhassan DM; Mamuda A; Abdurrahman A; Adamu SM; Mohammed AM; Ahmed AI; Sadiq GU; Alfa AM; Usman NM; Takai UI

doi:10.61386/imj.v15i3.277

Authors

Salahu D Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Abdullahi MM Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Abdullahi H Department of Obstetrics and Gynaecology, Aminu Kano Teaching Hospital Kano, Nigeria
Adeleke N Federal Medical Centre, Nguru, Yobe State, Nigeria
Adesope S Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Aliyu LD Department of Obstetrics and Gynaecology, Aminu Kano Teaching Hospital Kano, Nigeria
Hassan MM Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Alhassan DM Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Mamuda A Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Abdurrahman A Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Adamu SM Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Mohammed AM Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Ahmed AI Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Sadiq GU Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Alfa AM Department of Anaesthesia, Aminu Kano Teaching Hospital, Kano, Nigeria
Usman NM Department of Anaesthesia and Intensive Care, Abubakar Tafawa Balewa Teaching Hospital, Bauchi, Nigeria
Takai UI Department of Obstetrics and Gynaecology, Aminu Kano Teaching Hospital Kano, Nigeria

DOI:

https://doi.org/10.61386/imj.v15i3.277

Abstract

Tranexamic acid (TXA) is a commonly used antifibrinolytic drug during surgical procedures to reduce blood loss. An Inadvertent intrathecal injection of TXA may lead to serious side effects including seizures and ventricular fibrillation with reported fatalities. We report a case of an inadvertentintrathecal injection of TXA which occurred as a result of similarities in appearance between TXA and heavy bupivacaine ampoules. The patient had subarachnoid lavage after experiencing back pain, systemic hypertension followed by generalized tonic clonic seizures.