Aggressive central giant cell granuloma of the mandible: A case report and review of literature

Authors

  • Uchechukwu B. Eziagu Department of Histopathology, University of Uyo Teaching Hospital, Uyo, Akwa Ibom State, Nigeria
  • Arthur Nwashindi Department of Dental Surgery, Maxillofacial Surgery Unit, University of Uyo Teaching Hospital, Uyo, Akwa Ibom State, Nigeria
  • Ikwo J. Kudamnya Department of Histopathology, University of Uyo Teaching Hospital, Uyo, Akwa Ibom State, Nigeria

Keywords:

Aggressive central giant cell granuloma, Giant cell reparative granuloma, Mandible, Jawbone, Mass lesion

Abstract

Mandibular aggressive central giant cell granuloma is a rare non-neoplastic giant cell tumour characterised by pain, bone destruction, tooth root resorption, jawbone cortical perforation, and high recurrence rate. This is a case of a 10-year-old boy who presented to the Dental Surgical outpatient clinic of University of Uyo Teaching Hospital with a three-year history of left jaw swelling. The clinical diagnosis was fibrous dysplasia of the left hemi-mandible. Consequently, left hemi-mandibulectomy was performed, and subsequent histopathological diagnosis was aggressive central giant cell granuloma of the mandible. This article presents this rare diagnosis and explores its classification, aetiopathogenesis, clinico-pathological features and management.

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Published

01-05-2022

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